Maneva finished her education in 1966. Her classmates were Ilka Zafirova, Ruth Rafailova and many more famous Bulgarian actresses. Her debut was in 'Kaloyan'. First marriage was with the operator Nickolay Penchev. That relationship produced one daughter - Nadejda, born in 1969. Her famous movies are: 'Avtostop', 'Dami kanyat', '12 miga ot Tzvetana' (which is a documentary movie about her), 'Opasen char', 'Voynata na taralejite', 'Edna kaloriya nejnost', 'Izpepelyavane' and so on. Now she is married to Iavor Milushev, an actor and a politicion. In 2004 Tzvetana celebrated her 60th birthday.
Mrs Maneva has also played in the theatre. Her famous appearances are in 'Opera za Tri Grosha', 'Svekurva', 'Nora', 'Albena', 'Medeia' and so on. For her 60th birthday the theatre director - Margarita Mladenova invited Tzvetana and another famous Bulgarian actress - Maria Kavardjikova to play in David Hare's play 'Breath of Life' - 'I Chovekut Stana Jiva Dusha'.